منابع مشابه
Determination of Quantal Dose-Response Characteristics in Phenotypic Assays using Supervised Classification
We have designed and implemented a fully automatic, high-throughput screen against the causative parasite of the devastating illness, schistosomiasis, using computer vision and machine learning. The computer vision component segments (individually recognizes and delineates) schistosomula in brightfield micrographs, including touching and partially overlapping parasites. A learning model employi...
متن کاملEvaluation of chemosensitivity prediction using quantitative dose–response curve classification for highly advanced/relapsed gastric cancer
BACKGROUND The use of standard chemotherapy regimens has changed the application of chemosensitivity tests from all chemotherapy-eligible patients to those who have failed standard chemotherapy, which includes patients with highly advanced, relapsed, or chemoresistant tumors. METHODS We evaluated a total of 43 advanced primary and relapsed gastric cancers for chemosensitivity based on drug do...
متن کاملClassification of radiation effects for dose limitation purposes: history, current situation and future prospects
Radiation exposure causes cancer and non-cancer health effects, each of which differs greatly in the shape of the dose-response curve, latency, persistency, recurrence, curability, fatality and impact on quality of life. In recent decades, for dose limitation purposes, the International Commission on Radiological Protection has divided such diverse effects into tissue reactions (formerly termed...
متن کاملClassification: Biological Sciences - Population Biology When does high-dose antimicrobial chemotherapy prevent the evolution of resistance?
High-dose chemotherapy has long been advocated as a means of controlling 1 drug resistance in infectious diseases but recent empirical and theoretical studies have 2 begun to challenge this view. We show how high-dose chemotherapy engenders opposing 3 evolutionary processes involving the mutational input of resistant strains and their release 4 from ecological competition. Whether such therapy ...
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ژورنال
عنوان ژورنال: Journal of Epidemiology & Community Health
سال: 1998
ISSN: 0143-005X
DOI: 10.1136/jech.52.5.340